Fmoc-Gly-Gly-Phe-OtBu

SKU: orb1307426

Description

Fmoc-Gly-Gly-Phe-OtBu is a cleavable peptide linker used in constructing antibody-drug conjugates (ADCs) for targeted cancer therapy research. Its design facilitates drug release in both in vitro and in vivo experimental models, supporting the development of novel bioconjugates.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 236426-37-2
• MW: 557.64
• Purity: 99.82% (May vary between batches)
• Formula: C₃₂H₃₅N₃O₆
• SMILES: CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc12
• Target: PROTAC Linker,ADC Linker
• Solubility: 10% DMSO+90% Corn Oil:5 mg/mL (8.97 mM);DMSO:200 mg/mL (358.65 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cleavable, ADC Linker, ADC Linkers, ADCLinker, Antibody-drug conjugates linkers, FmocGlyGlyPheOtBu, Fmoc-Gly-Gly-Phe-OtBu, Fmoc Gly Gly Phe OtBu, Inhibitor, inhibit

Compound Identifiers

PubChem CID

11103667