Fluticasone propionate

SKU: orb1223965

Description

Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis.(In Vitro):Fluticasone propionate inhibits TNFα-induced E-selectin expression, with an IC50 of 1 nM.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 80474-14-2
• MW: 500.57
• Purity: >98% (HPLC)
• Formula: C₂₅H₃₁F₃O₅S
• SMILES: CCC(O[C@]1(C(SCF)=O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@@]3(F)[C@H]2C[C@H](F)C4=CC(C=C[C@@]43C)=O)=O
• Target: Estrogen Receptor/ERR
• Solubility: Ethanol: 5 mg/mL (9.98 mM); DMSO: 100 mg/mL (199.77 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Fluticasone 17-Propionate

Quick Database Links

Gene Symbol

Estrogen Receptor/ERR