Fluorometholone

SKU: orb1304332

Description

Fluorometholone is a synthetic corticosteroid used in ophthalmic formulations like FML and Flarex to treat inflammatory conditions of the eye's anterior segment, including post-refractive surgery. It is applied in research models to study anti-inflammatory mechanisms and steroid responses in both in vitro and in vivo ocular studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 426-13-1
• MW: 376.46
• Purity: 99.15% (May vary between batches)
• Formula: C₂₂H₂₉FO₄
• SMILES: [H][C@@]12CC[C@](O)(C(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](C)C2=CC(=O)C=C[C@]12C
• Target: Glucocorticoid Receptor
• Solubility: 10% DMSO+90% Corn Oil:2.5 mg/mL (6.64 mM);DMSO:55 mg/mL (146.1 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Oxylone, Delmeson, dry eye, corticosteroids, Cortilet, Fluoromethalone, Fluorometholone, GlucocorticoidReceptor, glucocorticoids, Glucocorticoid Receptor, Inhibitor, inhibit

Compound Identifiers

PubChem CID

9878