Fluoromethalone

SKU: orb1225071

Description

Fluorometholone is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone acetate ophthalmic suspension is indicated for use in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.(In Vitro):Fluorometholone (25-100 nM; 12 hours, 24 hours) increases the gene expression of MUC1, MUC4, MUC16 and MUC19 in the conjunctival and corneal epithelial cells through activation of glucocorticoid receptors.

Key Properties

• CAS Number: 426-13-1
• MW: 376.46
• Purity: >98% (HPLC)
• Formula: C₂₂H₂₉FO₄
• SMILES: CC(O[C@]1(C(C)=O)CCC2C3C[C@H](C)C4=CC(C=CC4(C)[C@@]3(F)C(O)CC12C)=O)=O
• Target: Others
• Solubility: Water: 30mg/L

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NSC 33001 | U-8614

Quick Database Links

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