Fluorofenidone

SKU: orb1940723

Description

Fluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.

Key Properties

• CAS Number: 848353-85-5
• MW: 203.216
• Purity: >98% (HPLC)
• Formula: C₁₂H₁₀FNO
• SMILES: Cc1ccc(=O)n(c1)-c1cccc(F)c1
• Solubility: In Vitro: DMSO : 140 mg/mL (688.94 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AKF-PD