Fluacrypyrim

SKU: orb3135782

Description

Fluacrypyrim is an ester-based acaricide and functions as a STAT3 inhibitor. It significantly enhances the activity of protein tyrosine phosphatases (PTPs) and suppresses leukemia cell growth by inducing substantial G1 phase arrest and significantly reducing the levels of cyclin D1 protein and mRNA. Fluacrypyrim selectively inhibits the STAT3 signaling pathway, leading to growth arrest and apoptosis in STAT3-dependent cancer cells. It mainly alleviates radiation-induced hematopoietic system damage by preventing apoptosis in hematopoietic stem cells (HSCs). Additionally, fluacrypyrim exhibits notable analgesic and anti-inflammatory effects by inhibiting uterine smooth muscle contraction and inflammatory responses.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 229977-93-9
• MW: 426.39
• Formula: C₂₀H₂₁F₃N₂O₅
• SMILES: C(\C(OC)=O)(=C/OC)/C1=C(COC=2C=C(C(F)(F)F)N=C(OC(C)C)N2)C=CC=C1
• Target: Apoptosis,STAT,MDM-2/p53,Phosphatase,Parasite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,STAT,MDM-2/p53,Phosphatase,Parasite