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FLT3/CDKs ligand-1

SKU: orb2646048

Description

Compound 14 acts as a bifunctional ligand that targets FLT3 and CDKs for proteasomal degradation, suppressing leukemia cell growth. It serves as a key precursor for synthesizing PROTAC FLT3/CDKs Degrader-1, a tool compound used in vitro to study targeted protein degradation in oncology research.

Research Area

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2452019-67-7
MW517.58
FormulaC26H31N9O3
SMILESO=C(OC(C)(C)C)N1CCN(CC2=CC=C(C=C2)NC(=O)C3=NNC=C3NC=4N=CN=C5NC=CC54)CC1
TargetLigands for Target Protein for PROTAC,CDK,FLT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information