FLT3-IN-32 TFA

SKU: orb3136545

Description

FLT3-IN-32 TFA is a potent FLT3 inhibitor with IC50 values of 2.40 nM and 3.83 nM against FLT3-ITD and FLT3-D835Y, respectively. It effectively inhibits the proliferation/survival of human MV4-11 cells with an IC50 of 0.07 nM. FLT3-IN-32 TFA is applicable in acute myeloid leukemia (AML) research.

Research Area

Cardiovascular Research, Immunology & Inflammation; Cell Biology, Signal Transduction

Key Properties

• CAS Number: 3047195-49-0
• MW: 629.58
• Formula: C₃₀H₃₀F₃N₅O₇
• SMILES: O=C(O)C(F)(F)F.O=C(NC1=NOC(=C1)C(C)(C)C)NC=2C=CC=3OC(=CC3C2)C(=O)C4=CC=5C(=CC=C(O)C5CN(C)C)N4
• Target: FLT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

FLT