FLT3-IN-21

SKU: orb2277977

Description

FLT3-IN-21 (LC-3) is a potent and selective FLT3 inhibitor with single-digit nM IC50 values, inducing G1 cell cycle arrest and apoptosis in FLT3-ITD-positive AML cells like MV-4-11. It demonstrates significant in vivo efficacy, achieving over 90% tumor growth inhibition in xenograft models, supporting its use in hematological cancer research.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• MW: 383.42
• Formula: C₂₀H₂₂FN₅O₂
• Target: Apoptosis,FLT,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,FLT,Others