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FLT3-IN-2

SKU: orb1307045

Description

FLT3-IN-2 is a potent small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3), exhibiting an IC50 value below 1 micromolar. This compound is a valuable research tool for investigating FLT3-driven signaling pathways in biochemical and cellular assays, and it has been utilized in preclinical studies exploring acute myeloid leukemia (AML).

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number923562-23-6
MW416.83
Purity98.53% (May vary between batches)
FormulaC21H16ClF3N4
SMILESFC(F)(F)c1ccc(CNc2ccc(Cc3c[nH]c4ncc(Cl)cc34)cn2)cc1
TargetFLT
SolubilityDMSO:50 mg/mL (119.95 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.8 mM)

Bioactivity

Target IC50
FLT3:<1 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cluster of differentiation antigen 135, CD135, inhibit, FLT3IN2, FLT-3-IN-2, FLT3-IN-2, FLT3 IN 2, FLT3, Fms like tyrosine kinase 3, Inhibitor

Similar Products

  • FLT3-IN-2 [orb1223642]

    >98% (HPLC)

    923562-23-6

    416.83

    C21H16ClF3N4

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 80.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 120.00
25 mg
$ 180.00
50 mg
$ 270.00
100 mg
$ 360.00
DispatchUsually dispatched within 5-10 working days
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