FLT3-IN-17

SKU: orb1686866

Description

FLT3-IN-17 is a potent, dual-action small molecule inhibitor targeting focal adhesion kinase (FAK) with an IC50 of 12 nM. It also potently inhibits FLT3 mutants, including D835Y (IC50 <0.5 nM), and modulates CYP activity. This compound is a valuable research tool for investigating oncogenic signaling in hematological and solid tumor models, both in vitro and in vivo.

Research Area

Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 2758999-62-9
• MW: 480.61
• Formula: C₂₃H₂₄N₆O₂S₂
• SMILES: N(C=1N=C2C(=CSC2=CN1)C3=CC(NS(C)(=O)=O)=CC=C3)C4=CC=C(C=C4)N5CCNCC5
• Target: FLT,Others,FAK,Cytochromes P450

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164627080