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FL442

SKU: orb2665477

Description

FL442 is a potent androgen receptor (AR) antagonist effective against both wild-type AR and the enzalutamide-resistant F876L mutant in prostate cancer models. It demonstrates favorable pharmacokinetics with a long half-life, prostate targeting, and inhibits LNCaP tumor growth at low plasma concentrations in vivo.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1431166-12-9
MW294.27
FormulaC15H13F3N2O
SMILESN#CC=1C=CC(=CC1C(F)(F)F)C2=NOC3CCCCC23
TargetAndrogen Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information