Firazorexton hydrate

• Catalog Number: orb2278508
• Category: Small Molecules
• Description: Firazorexton hydrate (TAK-994) is a brain-penetrant, orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM, effectively reducing wakefulness fragmentation and cataplexy-like episodes in mouse models of narcolepsy [1].
• CAS Number: 2861934-86-1
• Purity: 98.00%
• MW: 497.53
• SMILES: C([C@@H]1N(C(C(C)(C)O)=O)CC[C@@H]1NS(C)(=O)=O)C2=C(F)C(=CC=C2)C3=CC(F)=CC(F)=C3.O
• Formula: C₂₂H₂₅F₃N₂O₄S.3/2H₂O
• Biological Activity: Firazorexton hydrate (TAK-994) is a brain-penetrant and orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM. It effectively reduces wakefulness fragmentation and cataplexy-like episodes in mouse models of narcolepsy [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.