Fipexide

SKU: orb1225252

Description

Fipexide (Attentil, Vigilor) is a psychoactive drug of the piperazine chemical class which was developed in Italy in 1983. It was used as a nootropic drug in Italy and France, mainly for the treatment of senile dementia, but is no longer in common use due to the occurrence of rare adverse drug reactions including fever and hepatitis.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 34161-24-5
• MW: 388.85
• Purity: >98% (HPLC)
• Formula: C₂₀H₂₁ClN₂O₄
• SMILES: ClC1=CC=C(OCC(=O)N2CCN(CC3=CC4=C(OCO4)C=C3)CC2)C=C1
• Target: Dopamine Receptor
• Solubility: DMSO: 10 mM

Bioactivity

• In Vivo:
  Animal model: Kindled rats. Dosage: 10 mg/kg. Administration: Orally; 5-10 days. Result: Completely abolishes the memory deficit produced by kindling. Antagonized the amnestic effect of Pentylenetetrazole (PTZ)-kindling.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Dopamine Receptor