FINO2

SKU: orb1689828

Description

FINO2 is a potent and stable ferroptosis inducer that functions by inhibiting GPX4 activity, oxidizing ferrous iron, and triggering lipid peroxidation. It is a valuable research tool for studying ferroptosis mechanisms in both cellular and animal models of cancer and neurodegenerative diseases.

Research Area

Cell Biology

Key Properties

• CAS Number: 869298-31-7
• MW: 256.38
• Purity: 97.27% (May vary between batches)
• Formula: C₁₅H₂₈O₃
• SMILES: CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1
• Target: Ferroptosis
• Solubility: DMSO:90 mg/mL (351.04 mM)

Bioactivity

• In Vitro:
  FINO2 (10 µM; 24 h) induces ferroptosis in HT-1080 cells, demonstrating the iron dependency of lipid peroxidation .

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FINO 2, FINO2, FINO-2, Ferroptosis

Compound Identifiers

PubChem CID

23815485