Fialuridine

SKU: orb1299621

Description

Fialuridine (DRG-0098) is a DNA polymerase inhibitor studied for hepatitis B virus (HBV) treatment. It has demonstrated potent antiviral activity in both in vitro cell culture assays and in vivo animal models of HBV infection, supporting its investigation as a potential therapeutic agent.

Research Area

Cell Biology, Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 69123-98-4
• MW: 372.09
• Purity: 99.43% (May vary between batches)
• Formula: C₉H₁₀FIN₂O₅
• SMILES: OC[C@H]1O[C@H]([C@@H](F)[C@@H]1O)n1cc(I)c(=O)[nH]c1=O
• Target: DNA/RNA Synthesis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.69 mM);DMSO:10 mg/mL (26.88 mM)

Bioactivity

• In Vitro:
  Fialuridine (FIAU) blocks DNA synthesis in human cytomegalovirus and hepatitis B, as well as herpes simplex

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RNA Synthesis, RNASynthesis, DRG0098, DRG-0098, DRG 0098, DNA polymerase, DNA Synthesis, DNA/RNA Synthesis, DNASynthesis, Fialuridine, FIAU, Inhibitor, inhibit, NSC 678514, NSC678514, NSC-678514, Orthopoxvirus

Compound Identifiers

PubChem CID

50313