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FHND5032

SKU: orb3136148

Description

FHND5032 is an orally active miR-124 inducer that significantly enhances miR-124 expression in macrophages. It inhibits the PIK3R2/PI3K/Akt axis to block inflammatory signaling, facilitates macrophage reprogramming, and restores epithelial barrier function. FHND5032 alleviates colitis and reduces inflammatory burden in ulcerative colitis mouse models, making it useful for ulcerative colitis research.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Signal Transduction

Images & Validation

Key Properties

CAS Number3076057-63-8
MW339.70
FormulaC15H9ClF3N3O
SMILESFC(F)(F)OC1=CC=C(C=C1)NC=2N=CC3=CC=C(Cl)C=C3N2
TargetAntibacterial,Akt,Interleukin,PI3K

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information