FGIN-1-27

SKU: orb1305813

Description

FGIN-1-27 is a potent and selective translocator protein (TSPO) agonist with a Ki of 5.0 nM. Its ability to cross the blood-brain barrier makes it a valuable research tool for studying neuroinflammation, neurosteroidogenesis, and related neurological disorders in both cellular and animal models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 142720-24-9
• MW: 436.6
• Purity: 99.86% (May vary between batches)
• Formula: C₂₈H₃₇FN₂O
• SMILES: CCCCCCN(CCCCCC)C(=O)Cc1c([nH]c2ccccc12)-c1ccc(F)cc1
• Target: Others,GABA Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.29 mM);DMSO:4.37 mg/mL (10.01 mM)

Bioactivity

• Target IC50:
  PBR:5.0 nM(Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

convulsions, blood brain barrier, BBB, Isoniazid, inhibit, indoleacetamide, Inhibitor, PBR, FGIN 1 27, FGIN 1-27, FGIN127, FGIN-1-27, peripheral benzodiazepine receptor, peripheral benzodiazepine receptor (PBR)

Compound Identifiers

PubChem CID

132496