FGFR2-IN-1

SKU: orb1688733

Description

FGFR2-IN-1 is a selective small molecule inhibitor of FGFR1, FGFR2, and FGFR3 (IC50 = 460, 140, and 2200 nM, respectively). It is a useful research tool for investigating FGFR2-driven oncogenesis in both cellular and animal models of cancer. Its CAS number is 13460-73-81-1.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2677709-76-9
• MW: 357.41
• Purity: 98.99% (May vary between batches)
• Formula: C₂₂H₁₉N₃O₂
• SMILES: O=C(NC1=NNC=2C=C(C=CC12)C=3C=CC=C(OCC)C3)C=4C=CC=CC4
• Target: FGFR

Bioactivity

• Target IC50:
  FGFR2:140 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FGFR3, FGFR1, FGFR2

Compound Identifiers

PubChem CID

157049296