FGFR-IN-8

SKU: orb1685915

Description

FGFR-IN-8 is a potent, orally bioavailable inhibitor targeting wild-type and mutant FGFR isoforms with low nanomolar IC50 values. It induces apoptosis and demonstrates anti-tumor activity, supporting its use in preclinical cancer research for studying FGFR-driven malignancies in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2640217-64-5
• MW: 584.5
• Formula: C₂₇H₃₁Cl₂N₉O₂
• SMILES: N(C1=C(C=CC=N1)C=2N=C(NC3=CN(N=C3)C4CCN(C(C)C)CC4)N=CN2)C5=C(Cl)C(OC)=CC(OC)=C5Cl
• Target: Others,Apoptosis,FGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156730478