FGFR-IN-22

SKU: orb3136525

Description

FGFR-IN-22 (Compound 23) is an FGFR inhibitor with IC50 values of 0.631 nM for FGFR1, 1.26 nM for FGFR2, 0.851 nM for FGFR3, and 1 nM for FGFR4. It effectively inhibits cell proliferation dependent on FGFR1 and FGFR3 signaling pathways. FGFR-IN-22 is applicable in research related to cancers such as chronic lymphocytic leukemia (CLL).

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1431872-18-2
• MW: 460.46
• Formula: C₂₃H₂₁FN₈O₂
• SMILES: FC=1C(OC)=CC(OC)=CC1N(C2=NC3=NC(=CN=C3C=C2)C=4C=NN(C4)C)CC5=NC=CN5
• Target: FGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

FGFR