Ferroptosis inducer-8

SKU: orb3136400

Description

Ferroptosisinducer-8 is a ferroptosis (iron-dependent cell death) inducer with high selectivity against other cell death pathways. It induces ferroptosis by affecting ACSL4, GPX4, and FTH1, disrupting intracellular iron homeostasis and the GSH/GPX4 antioxidant defense system, leading to the accumulation of lipid peroxides. Ferroptosisinducer-8 also stimulates ROS production and can inhibit tumor growth, making it useful for research in triple-negative breast cancer (TNBC).

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research

Key Properties

• CAS Number: 3097194-74-3
• MW: 486.34
• Formula: C₂₂H₂₅Cl₂NO₇
• SMILES: C(N(C(CCl)=O)C1=CC(OC)=C(Cl)C(OC)=C1)C=2[C@@]3([C@@](C(C(OC)=O)=CO[C@H]3OC)(CC2)[H])[H]
• Target: Ferroptosis,Glutathione Peroxidase,ROS

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Ferroptosis,Glutathione Peroxidase,ROS