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Ferroptosis inducer-10

SKU: orb3173312

Description

Ferroptosisinducer-10 is an inducer of ferroptosis, capable of inhibiting the growth of A549 cells with an IC50 value of 0.76 μM. It functions by depleting glutathione (GSH), increasing reactive oxygen species (ROS) and malondialdehyde (MDA), and downregulating glutathione peroxidase 4 (GPX4) expression. Additionally, Ferroptosisinducer-10 induces cell cycle arrest at the G2/M phase and inhibits cell migration. This compound is applicable in cancer research, such as in studies of non-small cell lung cancer.

Research Area

Cell Biology, Metabolism Research

Images & Validation

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Ferroptosis inducer-10

Key Properties

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TargetGlutathione Peroxidase,Ferroptosis

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Quick Database Links

Gene Symbol
Glutathione Peroxidase,Ferroptosis

Protocol Information

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