Ferroptosis-IN-6

SKU: orb2566267

Description

Ferroptosis-IN-6 is a potent inhibitor that blocks ferroptotic cell death and prevents the oxidation of the lipid peroxidation sensor STY-BODIPY. It is a valuable research tool for studying ferroptosis mechanisms in models of ischemia-reperfusion injury, both in cellular and animal studies.

Research Area

Cell Biology

Key Properties

• CAS Number: 1517780-59-4
• MW: 227.3
• Purity: 99.84% (May vary between batches)
• Formula: C₁₅H₁₇NO
• SMILES: OC=1C(=CC=CC1C)NCC2=CC=C(C=C2)C
• Target: Ferroptosis
• Solubility: DMSO:15 mg/mL (65.99 mM)

Bioactivity

• Target IC50:
  Ferroptosis:25.5 nM (EC50)
• In Vivo:
  Ferroptosis-IN-6 can effectively protect mice from renal ischemia-reperfusion injury.
• In Vitro:
  Ferroptosis-IN-6 (compound 13) is a potent Ferroptosis inhibitor with an EC50 of 25.5 nM.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

82680089