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Ferroptosis-IN-23

SKU: orb3211316

Description

Ferroptosis-IN-23 is an inhibitor of ferroptosis (Ferroptosis) that acts synergistically by simultaneously activating Steap4 and glutathione peroxidase 4 (GPX4) to maintain iron metabolism homeostasis. It can reverse neuronal ferroptosis and suppress lipid ROS accumulation in cells. Ferroptosis-IN-23 inhibits ferroptosis in zebrafish, alleviating neuronal apoptosis, ROS accumulation, and dopaminergic neuron damage in a zebrafish model of Parkinson's disease. It is applicable for research into Parkinson's disease.

Images & Validation

Key Properties

TargetROS,Ferroptosis,Glutathione Peroxidase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information