Fedratinib hydrochloride hydrate

SKU: orb1298242

Description

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	1374744-69-0
MW	615.61
Purity	99.87%
Formula	C₂₇H₄₀Cl₂N₆O₄S
SMILES	O.Cl.Cl.Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C
Target	Apoptosis,JAK
Solubility	DMSO:120 mg/mL (194.93 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.5 mM);H2O:97 mg/mL (157.57 mM)

Bioactivity

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Target IC50	RET:48 nM\|JAK2 (V617F):3 nM\|JAK2:3 nM\|FLT3:15 nM

Storage & Handling

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Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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anti-proliferation, Apoptosis, anti-cancer, Inhibitor, FLT3, Fedratinib hydrochloride, Fedratinib hydrochloride Hydrate, Fedratinib hydrochloride hydrate, orally, inhibit, JAK2, JAK, JAK2V617F, JAK2 (V617F), Janus kinase, myeloproliferative, phosphorylation, RET, SAR 302503 hydrochloride, SAR 302503 hydrochloride hydrate, SAR 302503 hydrochloride Hydrate, TG-101348 hydrochloride, TG-101348 hydrochloride hydrate, TG-101348 hydrochloride Hydrate, STAT5

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Compound Identifiers

PubChem CID

67517580 ↗

Key Properties

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No computed properties available.

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