FD274

SKU: orb1819028

Description

FD274 is a potent dual PI3K/mTOR inhibitor active against PI3Kα/β/γ/δ and mTOR. It demonstrates significant in vitro antiproliferative activity in AML cell lines and exhibits dose-dependent in vivo antitumor efficacy in HL-60 xenograft models, supporting its research use in acute myeloid leukemia.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2641899-38-7
• MW: 480.9
• Formula: C₂₂H₁₄ClFN₆O₂S
• SMILES: O=S(=O)(NC=1C=C(C=NC1Cl)C2=CN=C3NN=C(C=4C=CN=CC4)C3=C2)C5=CC=C(F)C=C5
• Target: mTOR,PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168476157