FD1024

SKU: orb2277928

Description

FD1024 is a potent small molecule inhibitor of PIM kinases (PIM1/2/3 IC50s: 1.96-38.9 nM). It exhibits strong antiproliferative activity against AML cell lines like MV-4-11 and demonstrates in vivo antitumor efficacy in murine models, supporting its use in oncology and hematological cancer research.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 1422456-47-0
• MW: 430.47
• Formula: C₂₁H₂₀F₂N₄O₂S
• SMILES: FC1=C(C(F)=CC=C1)C2=NC(C(NC=3C(O[C@H]4CC[C@H](N)CC4)=CC=NC3)=O)=CS2
• Target: Pim

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71262763