FC 11

SKU: orb1690087

Description

FC 11 is a potent, reversible PROTAC degrader of FAK and its autophosphorylated form (pFAK Y397), with DC50 values in the picomolar range. This tool compound enables the study of FAK function and its role in cancer cell migration, invasion, and proliferation in both in vitro and in vivo research models.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2271035-37-9
• MW: 949.91
• Formula: C₄₁H₄₂F₃N₁₃O₉S
• SMILES: O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCN4C=C(C(NC5=CC=C(NC=6N=C(NCC7=C(N(S(C)(=O)=O)C)N=CC=C7)C(C(F)(F)F)=CN6)C=C5)=O)N=N4
• Target: FAK,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

154723926