FB49

SKU: orb2277700

Description

FB49 is a selective BAG3 inhibitor (Ki = 45 µM) that suppresses tumor cell proliferation, specifically inducing G1 cell cycle arrest, apoptosis, and autophagy in medulloblastoma models like HD-MB03 cells, while sparing normal peripheral mononuclear cells. Its mechanism supports research in oncology, particularly for studying protein quality control and cell death pathways in vitro.

Research Area

Cell Biology

Key Properties

• MW: 378.4
• Formula: C₁₇H₁₈N₂O₆S
• Target: Apoptosis,Autophagy

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,Autophagy