FB231

SKU: orb3173542

Description

FB231 is a Parkin activator that can induce mild mitochondrial stress, resulting in impaired mitochondrial function and activation of the integrated stress response (ISR). It reduces the threshold for PINK1/Parkin-mediated mitophagy induced by mitochondrial toxins and disrupts iron-dependent pathways. FB231 is applicable in research on neurological disorders, including Parkinson's disease.

Key Properties

• CAS Number: 2166045-37-8
• MW: 411.47
• Formula: C₂₄H₂₁N₅O₂
• SMILES: O=C(NC=1N=C(NC(=O)C=2C=CC=CC2C)N(N1)C=3C=CC=CC3)C=4C=CC=CC4C
• Target: Mitochondrial Metabolism,PTEN

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Mitochondrial Metabolism,PTEN