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FASN-IN-7

SKU: orb3173881

Description

FASN-IN-7 is a potent inhibitor of human fatty acid synthase (FASN). It effectively inhibits both the full-length FASN and the FASN KR domain, with IC50 values of 28 nM and 54 nM, respectively. FASN-IN-7 is capable of significantly suppressing the proliferation of various cancer cells. Additionally, it can increase the levels of malonyl-CoA in tumor tissues while reducing palmitic acid levels.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number1579514-16-1
MW493.61
FormulaC30H31N5O2
SMILESO=C1C2(N=C(N1C[C@H]3CN(C(=O)C4CC4)CC3)C5=CC=C(C=C5)C6=CC=C(C=C6)C7=CN(C)N=C7)CC2
TargetFatty Acid Synthase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information