Fasentin

SKU: orb1298778

Description

Fasentin is a small molecule inhibitor of the glucose transporter 1 (GluT1). It is used in research to study glucose metabolism, cancer cell energetics, and has been applied in both in vitro assays and in vivo models to investigate tumor growth inhibition.

Research Area

Cardiovascular Research, Cell Biology

Key Properties

• CAS Number: 392721-37-8
• MW: 279.64
• Purity: >98%
• Formula: C₁₁H₉ClF₃NO₂
• SMILES: CC(=O)CC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
• Target: Glucose transporter
• Solubility: Soluble in DMSO up to 28 mg/ml

Bioactivity

• Target IC50:
  GLUT4:68 μM (IC50)
• In Vitro:
  Fasentin has been described as a modulator of GLUT-1 and GLUT-4 transporters, thus inhibiting glucose uptake in some cancer cells.

Storage & Handling

• Storage: RT
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-angiogenic, Glucose transporter, glucose, GLUT4, GLUT, GLUT1, factor, G0/G1, FAS, Fasentin, Inhibitor, inhibit, N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide, necrosis, phase, tumor, transport

Compound Identifiers

PubChem CID

879520