Fascaplysin chloride

SKU: orb1700619

Description

Fascaplysin is a selective CDK4/cyclin D1 inhibitor (IC50 = 0.35 µM) that triggers caspase-dependent apoptosis and autophagy crosstalk via PI3K/AKT/mTOR pathway suppression. This mechanism has been demonstrated in vitro in human leukemia HL-60 cells, supporting its research use in oncology and cell cycle studies.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 114719-57-2
• MW: 306.75
• Formula: C₁₈H₁₁ClN₂O
• SMILES: [Cl-].O=C1C2=C(C=CC=C2)[N+]2=C1C1=C(C=C2)C2=CC=CC=C2N1
• Target: Apoptosis,Autophagy,Others,Reactive Oxygen Species

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

73292