FAP-PI3KI1

SKU: orb1982974

Description

FAP-PI3KI1 is a fibroblast-activated protein (FAP)-directed small molecule that selectively inhibits PI3K in FAP-expressing cells, such as those in idiopathic pulmonary fibrosis (IPF). It demonstrates efficacy in reducing collagen production and deposition in relevant in vitro and in vivo fibrotic disease models.

Research Area

Cell Biology

Key Properties

• CAS Number: 2415941-98-7
• MW: 1177.19
• Formula: C₅₂H₄₈F₄N₁₀O₁₂S₃
• SMILES: COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nccc(-c3ccc(COC(=O)OCCSSC[C@H](NC(=O)CCC(=O)NCc4cc(ccn4)C(=O)N[C@@H](C)C(=O)N4CC(F)(F)C[C@H]4C#N)C(O)=O)nc3)c2c1
• Target: Others,PI3K

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166642633