FAK-IN-26

SKU: orb3027707

Description

FAK-IN-26 is a blood-brain barrier-penetrating inhibitor of Focal Adhesion Kinase (FAK) with an IC50 of 0.87 nM. It significantly reduces tumor cell viability, cancer stem cell activity, and cell migration in A549 and SKOV-3 cell lines. FAK-IN-26 exhibits potent anticancer activity, achieving tumor inhibition rates of 59.15% and 57.9% in A549 and SKOV-3 tumor mouse models, respectively.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 2801785-12-4
• MW: 460.30
• Formula: C₂₀H₁₉BrFN₅O₂
• SMILES: O=C(NC)C=1C=CC=CC1NC2=NC(=NC=C2Br)NC3=CC=C(OCCF)C=C3
• Target: FAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

FAK