FAK-IN-10

SKU: orb1905814

Description

FAK-IN-10 is a small molecule inhibitor of Focal Adhesion Kinase (FAK) with an enzymatic IC50 of 76.3 µM. It demonstrates potent anti-proliferative activity in cellular assays, exhibiting IC50 values of 4.23 µM in MCF-7 breast cancer cells and 0.78 µM in A431 epidermoid carcinoma cells, supporting its use in cancer research.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 491839-65-7
• MW: 376.23
• Purity: 99.78% (May vary between batches)
• Formula: C₁₅H₁₀BrN₃O₂S
• SMILES: O=C(C1=CC=C(Br)C=C1)CSC2=NN=C(O2)C=3C=CN=CC3
• Target: FAK
• Solubility: DMSO:7.5 mg/mL (19.93 mM)

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FAK, FAKIN10, FAK-IN-10

Compound Identifiers

PubChem CID

1203917