Fabomotizole dihydrochloride

• Catalog Number: orb1739407
• Category: Small Molecules
• Description: Fabomotizole dihydrochloride
• Purity: 98.00%
• MW: 380.33
• Biological Activity: Fabomotizole, also known as Afobazole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors.
• CAS Number: 189638-30-0
• Formula: C₁₅H₂₃Cl₂N₃O₂S
• SMILES: Cl.Cl.CCOc1ccc2nc(SCCN3CCOCC3)[nH]c2c1
• Storage: -20°C
• Note: For research use only