F9170 TFA

SKU: orb1980094

Description

F9170 is an antiviral peptide derived from HIV-1 gp41 (aa 789-803) that targets the LLP1 domain. It inhibits HIV-1 IIIB infection in MT-2 cells (EC50: 0.19 µM) and reduces viral load in SHIV-infected rhesus macaques at 3 mg/kg, supporting its study in HIV pathogenesis and antiviral development.

Research Area

Immunology & Inflammation, Infectious Disease & Virology, Protein Biochemistry

Key Properties

• Target: HIV Protease
• MW: 1983.30
• Formula: C₁₀₀H₁₃₅N₂₁O₂₂.XCF₃COOH
• SMILES: OC(C(F)(F)F)=O.OC(C=C1)=CC=C1C[C@H](NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@@H](NC(CN)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(O)=O)CC4=CNC5=CC=CC=C45)=O)CC6=CC=C(C=C6)O)=O)=O)=O)=O)=O)CC7=CNC8=CC=CC=C78)=O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171361294