F7H

SKU: orb1944742

Description

F7H is a potent small molecule antagonist of the Frizzled-7 receptor (FZD7), exhibiting an IC50 of 1.25 μM by targeting its transmembrane domain. It demonstrates potential antitumor and bacteriostatic activities in preclinical research, making it a valuable tool for studying Wnt signaling in cancer and microbiological contexts both in vitro and in vivo.

Research Area

Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 897109-93-2
• MW: 463.55
• Purity: 99.85% (May vary between batches)
• Formula: C₂₄H₁₈FN₃O₂S₂
• SMILES: O=C(NC1=CC=C(SCC(=O)NC2=NC(=CS2)C=3C=CC=CC3)C=C1)C4=CC=C(F)C=C4
• Target: Wnt/beta-catenin,Antibacterial
• Solubility: DMSO:50 mg/mL (107.86 mM)

Bioactivity

• Target IC50:
  Frizzled receptor:1.25 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Wnt/b-catenin, Wnt/betacatenin, Wnt, Wnt/β-catenin, βcatenin, FZD7, F7H, Bacterial, bcatenin, betacatenin, beta-catenin

Compound Identifiers

PubChem CID

20169956