F5446

SKU: orb1737604

Description

F5446 is a selective SUV39H1 inhibitor that induces apoptosis in colorectal cancer cells by epigenetically upregulating Fas expression via H3K9me3 removal from its promoter. It has been utilized in vitro to study histone methylation's role in cancer immunology and cell death pathways.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 2304465-89-0
• MW: 552.94
• Purity: 98.56% (May vary between batches)
• Formula: C₂₆H₁₇ClN₂O₈S
• SMILES: COC(=O)C1=CC2=C(N1S(=O)(=O)C1=CC=C(Cl)C=C1)C(=O)C(=O)C1=C2C(=CN1)C(=O)OCC1=CC=CC=C1
• Target: Histone Methyltransferase,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138482841