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Catalog Number | orb1304213 |
---|---|
Category | Small Molecules |
Description | Ezutromid |
CAS Number | 945531-77-1 |
Purity | 99.19% |
MW | 337.39 |
SMILES | S(CC)(=O)(=O)C=1C=C2N=C(OC2=CC1)C3=CC4=C(C=C3)C=CC=C4 |
Formula | C19H15NO3S |
Biological Activity | Ezutromid (BMN 195) is a translation modulator of Small utrophin (EC50: 0.4 uM). Ezutromid is an orally bioavailable small molecule that transcriptionally upregulates the utrophin gene, increasing both utrophin mRNA and protein. Through this action, Ezutromid increases muscle function in dystrophin-deficient MDX mice, a mouse model of muscular dystrophy. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[945531-77-1] | |
337.392303705215 | |
C19H15NO3S |
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