EZH2-IN-9

SKU: orb1685832

Description

EZH2-IN-9 is a potent small molecule inhibitor targeting EZH2, including its oncogenic SET domain mutations. It reduces aberrant H3K27me3 levels and demonstrates anti-tumor activity in research models of cancers such as lymphoma and breast cancer, both in vitro and in vivo.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2700897-24-9
• MW: 596.09
• Formula: C₂₈H₃₂ClF₂N₃O₅S
• SMILES: CC1=C2C(OC(C)(O2)[C@@H]3CC[C@@H](C(=O)N4CC(F)(F)C4)CC3)=C(Cl)C=C1C(NCC5=C(SC)C=C(C)NC5=O)=O
• Target: Others,Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156852126