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EZH2-IN-3

SKU: orb1702286

Description

EZH2-IN-3 is a potent, dual inhibitor of the histone methyltransferases EZH2 and EZH1. It selectively suppresses the proliferation of diffuse large B-cell lymphoma (DLBCL) cells in vitro and has demonstrated efficacy in xenograft models, making it a valuable chemical probe for oncology and epigenetics research.

Research Area

Epigenetics & Chromatin

Images & Validation

Key Properties

CAS Number1377997-28-8
MW490
FormulaC27H28ClN5O2
SMILESC(#N)C1=C(C=CC=C1OC2=C(Cl)C=C(C(NC3CC(C)(C)NC(C)(C)C3)=O)C=C2)C=4C=CN=NC4
TargetOthers,Histone Methyltransferase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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EZH2-IN-3 (orb1702286)

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