EZH2-IN-22

SKU: orb2814396

Description

EZH2-IN-22 is a highly potent small molecule inhibitor of EZH2, demonstrating sub-nanomolar IC50 values against both wild-type and mutant (Y641N, Y641F) forms. Its robust antiproliferative activity supports its use in vitro for epigenetic cancer research and in vivo for studying oncogenic mechanisms in preclinical models.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2766231-05-2
• MW: 666.8
• Formula: C₃₆H₅₀N₄O₈
• SMILES: C(=C\C(O)=O)\C(O)=O.N(CC)(C1=C(C)C(C(NCC2=C(C)C=C(C)NC2=O)=O)=CC(O[C@@H]3C[C@H](C3)N4CCCCC4)=C1)C5CCOCC5
• Target: Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677399