(E/Z)-GSK-3β inhibitor 1

SKU: orb1298306

Description

This small molecule is a potent and selective glycogen synthase kinase 3β (GSK-3β) inhibitor. It has demonstrated significant antidiabetic efficacy in research models and is used in studies of type 2 diabetes, neurodegenerative diseases, and Wnt/β-catenin signaling pathways in both cellular and animal experiments.

Research Area

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3367-88-2
• MW: 222.24
• Purity: 99.80% (May vary between batches)
• Formula: C₁₄H₁₀N₂O
• SMILES: O=C1Nc2ccccc2\C1=C\c1ccccn1
• Target: GSK-3
• Solubility: DMSO:49 mg/mL (220.48 mM)

Bioactivity

• Target IC50:
  GSK-3β:4.9 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(E/Z)-GSK-3b inhibitor 1, (E/Z)-GSK-3beta inhibitor 1, (E/Z)GSK3β inhibitor 1, (E/Z)-GSK-3β inhibitor 1, (E/Z) GSK 3β inhibitor 1, GSK-3, GSK3, GSK-3b inhibitor 1, GSK-3β inhibitor 1, GSK-3beta inhibitor 1, GSK-3β

Compound Identifiers

PubChem CID

5796182