(E/Z)-BIO-acetoxime

SKU: orb1688148

Description

(E/Z)-BIO-acetoxime is a potent and selective GSK-3 α/β inhibitor with IC50 values of 10 nM, demonstrating significant selectivity over CDK5, CDK2, and CDK1. This small molecule is a valuable research tool for investigating GSK-3's role in cellular signaling, neurodegenerative diseases, and diabetes in both in vitro and in vivo models.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 740841-15-0
• MW: 398.21
• Formula: C₁₈H₁₂BrN₃O₃
• SMILES: N(OC(C)=O)=C1C(NC=2C1=CC=CC2)=C3C=4C(NC3=O)=CC(Br)=CC4
• Target: Others,GSK-3,CDK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

136218974