Exatecan Intermediate 7

SKU: orb2663888

Description

Exatecan Intermediate 7 is a key synthetic precursor for the potent topoisomerase I inhibitor Exatecan (DX-8951; IC50 = 2.2 μM). This intermediate is crucial for preparing the payload in Antibody-Drug Conjugates (ADCs) for targeted cancer therapy research, supporting both in vitro biochemical and in vivo preclinical studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 182182-32-7
• MW: 264.25
• Formula: C₁₃H₁₃FN₂O₃
• SMILES: O=C1C=2C(=CC(F)=C(C2CCC1=NO)C)NC(=O)C
• Target: ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162678865