Evo312

SKU: orb2663565

Description

Evo312 is a dose-dependent PKCβI inhibitor (IC50 = 117.34 nM) that suppresses PKCβI protein expression, inducing cell cycle arrest and apoptosis. It demonstrates potent antiproliferative activity in pancreatic cancer cells, including gemcitabine-resistant lines, and shows antitumor efficacy in mouse xenograft models.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2820245-53-0
• MW: 361.39
• Formula: C₂₁H₁₉N₃O₃
• SMILES: O=C(OC=1C=CC=2NC3=C(C2C1)CCN4C(=O)C=5C=CC=CC5N(C)C34)C
• Target: Apoptosis,PKC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171457793