Eupatorin

SKU: orb1300128

Description

Eupatorin is a bioactive flavonoid with demonstrated antiproliferative, cytostatic, and antiangiogenic properties, notably against breast cancer cell lines like MDA-MB-468 via CYP1 metabolism. It induces apoptosis through both intrinsic and extrinsic pathways involving ROS and exhibits significant anti-inflammatory activity, supporting its research in oncology and inflammation studies.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 855-96-9
• MW: 344.32
• Purity: 99.98% (May vary between batches)
• Formula: C₁₈H₁₆O₇
• SMILES: COc1ccc(cc1O)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
• Target: Cytochromes P450,Apoptosis
• Solubility: H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.9 mM);DMSO:10 mg/mL (29.04 mM)

Bioactivity

• In Vivo:
  Balsalazide is a new 5-aminosalicylic acid (5-ASA) containing prodrug. High dose balsalazide (3.0 g twice daily) was superior in maintaining remission in patients with ulcerative colitis compared with a low dose (1.5 g twice daily) or a standard dose of mesalazine (0.5 g three times daily). All three treatments were safe and well tolerated . Balsalazide is approved for the treatment of mild-to-moderate active UC. It is efficacious for the induction of remission in mild to moderate UC and has a favorable safety profile, with the added advantages of greater efficacy of remission induction and rapidity of onset .
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Eupatorin, Inhibitor, inhibit, CYP1

Compound Identifiers

PubChem CID

97214